Zack Greinke vs Johan Santana: Career Stats Comparison

Zack Greinke and Johan Santana are close to even, splitting the 8 scored categories on this page 4–4 (8 further counting totals are shown but not scored). Zack Greinke played 2004–2023 as a pitcher; Johan Santana played 2000–2012 as a pitcher.

ERA (Earned Run Average):
Earned runs allowed per nine innings pitched: (ER × 9) ÷ IP. The primary measure of pitching effectiveness.
W (Wins):
Games credited to a pitcher whose team took a lead it never surrendered while he was the pitcher of record.
SO (Strikeouts):
For a batter, times retired on a third strike; for a pitcher, batters retired on a third strike.
WHIP (Walks and Hits per Inning Pitched):
Baserunners allowed per inning: (BB + H) ÷ IP. Under 1.00 is elite.

Data updated

Zack Greinke (2004–2023) and Johan Santana (2000–2012) — both debuted in the 2000s. Zack Greinke finished with 225 wins and 2,979 strikeouts; Johan Santana finished with 139 wins and 1,988 strikeouts. The table below sets out their careers line by line.

Quick answer

  • Who leads the career comparison? Neither — they split the 8 scored categories 4–4.
  • Who had the better ERA? Johan Santana, with 3.20 to Zack Greinke's 3.49.
  • Who won more games? Zack Greinke, with 225 to Johan Santana's 139.
  • Who recorded more strikeouts? Zack Greinke, with 2,979 to Johan Santana's 1,988.
  • Who had the better WHIP? Johan Santana, with 1.13 to Zack Greinke's 1.17.
  • How many innings did each pitch? Zack Greinke 3,389.1, Johan Santana 2,025.2.
  • Who threw more shutouts? Johan Santana, with 10 to Zack Greinke's 5.
Even 4–4 across 8 scored categories
Pitcher PIV edge Zack Greinke +9,514
Read the verdict ↓

Zack Greinke

Pitcher · 2004–2023
Wins
225
Losses
156
Strikeouts
2,979
ERA
3.49
WHIP
1.17
IP
3,389.1
View Zack Greinke's full profile →

Johan Santana

Pitcher · 2000–2012
Wins
139
Losses
78
Strikeouts
1,988
ERA
3.20
WHIP
1.13
IP
2,025.2
View Johan Santana's full profile →

Career Stats Side-by-Side

Every cell below is a career total or career rate. Cells highlighted in green mark the player who leads that line. Lower ERA, WHIP and BB/9 lead; higher K/9 leads. 8 of the 16 lines below are scored; the other 8 are shown but not scored. Games, starts and innings measure playing time, and losses, walks and hits allowed track how long someone pitched, so they are left unmarked, as is any line where both players are at zero. Rate stats are not era-adjusted, so read them against the run environment each player worked in, or use the PIV card below, which is adjusted.

Zack Greinke vs Johan Santana: Career Stats Comparison — Career Stats Side-by-Side
Statistic Zack Greinke Johan Santana
Wins Leads: 225 139
Losses not scored 156 78
Games not scored 586 360
Games Started not scored 541 284
Complete Games Leads: 17 15
Shutouts 5 Leads: 10
Saves not scored 1 1
Strikeouts Leads: 2,979 1,988
Walks not scored 762 567
Hits Allowed not scored 3,207 1,726
Home Runs Allowed not scored 367 220
Innings Pitched not scored 3,389.1 2,025.2
ERA 3.49 Leads: 3.20
WHIP 1.17 Leads: 1.13
K/9 7.91 Leads: 8.83
BB/9 Leads: 2.02 2.52

PIV Comparison

By PIV (Player Impact Value), Zack Greinke leads Johan Santana 58,246 to 48,732 — a longevity gap rather than a per-season one: Zack Greinke played 20 seasons to Johan Santana's 12, while Johan Santana carries the higher per-season figure (4,061 to 2,912). PIV adjusts each season to league baselines, so it's the cleanest way to compare careers across eras.

Zack Greinke
58,246
Career Pitcher PIV · 2,912 per season (20 seasons)
Johan Santana
48,732
Career Pitcher PIV · 4,061 per season (12 seasons)

How PIV is calculated →

Peak Seasons

The best single seasons each player produced, ranked by ERA among qualified workloads (120+ innings).

Zack Greinke — top 3 seasons by ERA (lower is better)

20151.66 ERA19-3, 200 K in 222 IP
20092.16 ERA16-8, 242 K in 229 IP
20132.63 ERA15-4, 148 K in 177 IP

Johan Santana — top 3 seasons by ERA (lower is better)

20082.53 ERA16-7, 206 K in 234 IP
20042.61 ERA20-6, 265 K in 228 IP
20062.77 ERA19-6, 245 K in 233 IP

Verdict

Zack Greinke and Johan Santana split the 8 scored categories on the head-to-head card 4-4. On the raw scoreboard neither has the edge. PIV, which is era-adjusted, grades Zack Greinke higher. Click through to each profile for the full season-by-season breakdown.

Related Matchups

How the Zack Greinke and Johan Santana careers compare

From 2004 through 2012, Zack Greinke and Johan Santana were in the majors together. Zack Greinke has the far longer record, 586 games against 360 across 20 and 12 PIV seasons, which inflates every career total. The green cells for Johan Santana are shutouts (10 to 5), ERA (3.20 to 3.49), and WHIP (1.13 to 1.17). The per-nine rows read 7.91 strikeouts and 2.02 walks for Zack Greinke, 8.83 and 2.52 for Johan Santana. Zack Greinke was mainly a starter (541 starts in 586 games), and Johan Santana was mainly a starter (284 starts in 360 games). In WHIP, Johan Santana's 1.13 beats Zack Greinke's 1.17.

Zack Greinke vs Johan Santana: Frequently Asked Questions

Who was better, Zack Greinke or Johan Santana?
By the career statistics compared on this page, neither leads: they split the 8 scored categories 4–4.
Who had the better ERA?
Johan Santana, with 3.20 to Zack Greinke's 3.49.
Who won more games?
Zack Greinke, with 225 to Johan Santana's 139.
Who recorded more strikeouts?
Zack Greinke, with 2,979 to Johan Santana's 1,988.
Who had the better WHIP?
Johan Santana, with 1.13 to Zack Greinke's 1.17.

See These Players in Another Era